The safety and the therapeutic efficacy of ?-dihydroergocriptin in the treatment of Parkinson's disease by multi-center clinical trial
- VernacularTitle:?-二氢麦角隐亭治疗帕金森病的临床多中心观察
- Author:
Xinde WANG
;
Xiangru SUN
;
Yi LUO
;
Jizuo WANG
;
Yuping JIANG
;
Shengdi CHEN
- Publication Type:Journal Article
- Keywords:
Parkinson's disease;
Dopaminergic agonist;
? dihydroergocriptin
- From:
Chinese Journal of Geriatrics
1995;0(02):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To study the therapeutic efficacy of dopaminergic agonists,? dihydroergocriptin(Cripar) by multiple center opened trial Methods Sixty cases of Parkinson's disease were divided into two groups: monotherapy group(27 cases) and combined therapy group(33 cases) The improvement in both groups after therapy was observed Results Patients undergone monotherapy were treated with ? dihydroergocriptin and those undergone combined therapy were treated with combined use of ? dihydroergocriptin and L doparmine All patients after treatment showed improvement of clinical symptoms There were 7 patients (28 0%) in the monotherapy group and 13 patients (39 4%) in the combined therapy group markedly improved Evaluation of therapeutic improvement by modified UPDRS revealed that the average scores was 5 01 in monotherapy group and was 6 39( P
