The clinical significance of elevated plasma and urinary interleukin-6 level in type II diabets mellitus
- VernacularTitle:Ⅱ型糖尿病患者血、尿白介素-6变化的意义
- Author:
Jingze HUANG
;
Jian WANG
;
Peiji HUANG
;
Al ET
- Publication Type:Journal Article
- Keywords:
Type 2 diabetes mellitus Diabetic nephrophathy Cytokine Interleukin 6
- From:
Chinese Journal of Immunology
2001;0(10):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To explore the clinical significance of interleukin 6(IL 6) in pathogenesis of diabetic nephropathy by comparing the plasma and urinary level of IL 6 in patients with type 2 diabetes mellitus(DM).Methods:The plasma and urinary level of IL 6 were measured with radioimmunoassay in 20 normal controls(NC group) and 45 cases of type 2 DM,including 23 cases without albuminuria(DSM group) and 22 cases with trace albuminuria(EDN group).Results:(1)The plasms and urinary level of IL 6 markly elevated in SDM group(P