Preventive effect of hepatic arterial infusion (DDS) against post-operative recurrence of hepato-cellular carcinoma
- VernacularTitle:肝动脉埋泵化疗预防肝癌术后复发的作用
- Author:
Jian-Min GUO
;
Yun-Li ZHANG
;
Li-Xing ZHOU
;
- Publication Type:Journal Article
- Keywords:
hepatocellular carcinoma;
hepatic arterial infusion chemotherapy;
recurrence;
survival rate
- From:China Oncology
2001;0(05):-
- CountryChina
- Language:Chinese
-
Abstract:
Purpose:To explore the preventive effect of hepatic arterial infusion (DDS) against recurrence of hepato- cellular carcinoma (HCC) after radical resection.Methods:From Jan,1996 to May,1998,287 patients of HCC after radical resection were randomly divided into four groups:intra-hepatic arterial infusion(97),intra-portal vein(80),intra-hepatic artery and portal vein (60),control (50).All patients received chemotherapy for two years and observed for postoperative recurrence of HCC.Results:The postoperative recurrence rate of HCC with intra-hepatic arterial infusion was significantly lower than that of intra-portal vein (P0.05).The 1～、2～ and 3～year survival rate of intra-hepatic arterial infusion was significantly higher than any of the other groups.Conclusions:Intra-hepatic arterial infusion (DDS) through gastro-duodenal artery can effectively pro- long the postoperative survival and decrease the post-operative recurrence rate of HCC.The preventive method of DDS through gastro-duodenal artery was safer and effective.
