Study of CD40 and CD80 on peripheral blood dendritic cells in patients with chronic hepatitis B in vitro
- VernacularTitle:慢性乙型肝炎患者外周血树突细胞CD40、CD80表达和免疫活性的体外研究
- Author:
Yuqian ZHOU
;
Jun ZHAN
;
Qingli DENG
;
Al ET
- Publication Type:Journal Article
- Keywords:
Dendritic cells Hepatitis B virus
- From:
Chinese Journal of Immunology
2000;0(09):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To study the relation between the costimulating molecules CD40,CD80 on DC and their antigen presentation function in patients with chrnic HBV infection .Methods:The DC from healthy donors and patients were stained with anti human specific mouse monoclonal antibodies conjugated with fluorescein isothiocyanate(FITC) respectively.Mouse McAb used were anti HLA ABC,HLA DR,CD1a,CD14,CD40,CD80.Results:There are no remarkable difference in MHC I?MHC II between two groups;remarkable difference was showed in CD40(P