Evaluation of intravenous and intraperitoneal chemotherapy in advanced gastric cancer
- VernacularTitle:晚期胃癌静脉合并腹腔化疗近期疗效观察
- Author:
Haijun ZHONG
;
Lin SUN
;
Yipin ZHANG
;
- Publication Type:Journal Article
- Keywords:
advanced gastric cancer;
intravenous chemotherapy;
intraperitoneal chemotherapy
- From:China Oncology
1998;0(04):-
- CountryChina
- Language:Chinese
-
Abstract:
Purpose:To evaluate the immediate therapeutic effects and toxicities of intraperitoneal versus intravenous chemotherapy in advanced gastric cancer.Methods:Sixty one patients were treated with intravenous chemotherapy of leucovorin (CF) , fluorouracil ( 5 Fu) etoposide (Vp16) and intraperitoneal chemotherapy of cis platinum (DDP) in advanced gastric cancer. The short term effects and toxicities were observed.Results:The overall response rate was 57.4% and the complete response rate was 9.8% of the 61 patients .Leukopenia was observed in 95.1%, thrombocy topentia were observed in 27.8% of patients . Other side effects were uncommon.Conclusions:Intravenous chemotherapy of ELF and intraperitoneal chemotherapy of DDP were effective for advanced gastric cancer and are worthy to be further studied.
