Expression of tansforming growth factor-? and tansforming growth factor-? receptor in colorectal adenocarcinoma
- VernacularTitle:大肠癌组织中转化生长因子-?及其受体的表达
- Author:
Jiadong LI
;
Wenfang LIU
;
Yuezu FAN
;
Al ET
- Publication Type:Journal Article
- Keywords:
tansforming growth factor ?;
tansforming growth factor ? receptor;
colorectal adenocarcinoma;
immunohistochemistry
- From:
China Oncology
2001;0(03):-
- CountryChina
- Language:Chinese
-
Abstract:
Purpose:To investigate the relationship between the expression tansforming growth factor ?(TGF ?) and the differentiation, invasion of colorectal adenocarcinoma.Methods:To observe the expression of transforming growth factor ? and transforming growth factor ? receptor in 68 samples of colorectal adenocarcinoma with immunohistochemical technique. Results:The cells with positive reaction of TGF ? antibody were scattered in the stroma. The cells with infiltrative growth had positive TGF ? staining.Conclusions:It was indicated that TGF ? might play an important role in the invasion and metastasis of colorectal adenocarcinoma.