Significance of VEGF investigation in combination with SccAg in patients with cervical carcinoma
- VernacularTitle:宫颈癌患者中联合检测血清VEGF及SccAg的意义
- Author:
Yanna ZHANG
;
Changqing ZHANG
;
Hua WANG
;
Al ET
- Publication Type:Journal Article
- Keywords:
cervical carcinoma;
VEGF;
Scc Ag;
diagnosis;
prognosis
- From:China Oncology
2001;0(03):-
- CountryChina
- Language:Chinese
-
Abstract:
Purpose:Exploring for sensitive tumor markers of cervical carcinoma to decide correct program of treatment, and to predict the prognosis. Methods:The sera from 37 patients with cervical carcinoma, 26 patients with leiomyoma were obtained from Jul. 1999 to Jan. 2001. A quantitative enzyme linked immunosorbent assay (ELISA) was performed to measure the concentrations of S VEGF and a micropartical enzyme immunoassay (MEIA) was performed to measure the concentrations of Scc Ag. The X 2 Test, the t Test, the analysis of variance and the multivariated analysis were used as statistical analysis. Results: The mean S VEGF level in patients with cervical carcinoma was significantly higher than in patients with leiomyoma ( P 0.05), the positive rate of its expression in cervical carcinoma was 67.56%. Conclusions:The S VEGF and Scc Ag can be used as prognosis indicators, and also as for post operative radiotherapy in cervical carcinoma.
