Ondansetron plus dexamthasone in anti-emesis induced by cisplatin containing chemotherapy
- VernacularTitle:国产昂丹司琼加地塞米松防治顺铂化疗引起的呕吐
- Author:
Guangyao ZHANG
;
- Publication Type:Journal Article
- Keywords:
Ondansetron;
DDP chemotherapy;
Emesis
- From:
China Oncology
2001;0(03):-
- CountryChina
- Language:Chinese
-
Abstract:
Purpose:To evaluate the efficacy of ondansetron plus dexamethasone compared with metoclopramide plus dexamethasone against emesis induced by cisplatin (DDP) containing chemotherapy.Methods:53 malignant tumor patients received DDP containing chemotherapy. DDP was 20 mg/m 2 ,qd,from the first day to the fifth day;ondansetron was 4 mg plus dexamethasone 5 mg,qd,from the first day to the fifth day; metoclopramide was 10 mg plus dexamethasone 5mg,qd,from the first day to the fifth day. Results:The anti emetic rate of ondansetron plus dexamethasone was 82.6%,which was higher than that of metoclopramide plus dexamthasone (44.5%, P
