Advances in multidrug resistance mechanisms in lung cancer
- VernacularTitle:肺癌多药耐药性机制研究进展
- Author:
Jie CHEN
;
Guisheng QIAN
;
Guijun HUANG
;
- Publication Type:Journal Article
- Keywords:
lung neoplasms;
chemotherapy;
multidrug resistance
- From:
China Oncology
2001;0(03):-
- CountryChina
- Language:Chinese
-
Abstract:
Chemotherapy for lung cancer is expected to prolong the survival of lung cancer patients. multidrug resistance is considered to be a major cause of failure of treatment. Many multidrug resistance mechanisms have contributed to lung cancer drug resistance, such as P glycoprotein (P gp), multidrug resistance associated protein (MRP), lung resistance related protein (LRP). The drug efflux pump mechanisms are the focus of recent researches.
