Genotyping of ABO blood group and its application
- VernacularTitle:ABO血型基因分型及应用
- Author:
Jiongcai LAN
;
Qingbao MENG
;
Yinze ZHANG
;
Al ET
- Publication Type:Journal Article
- Keywords:
ABO blood group Polymerase chain reaction sequecific primer(PCR SSP) Genotyping
- From:
Chinese Journal of Immunology
1985;0(06):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To study on significance of ABO genotyping.Methods:To use the methods of polymerase chain reaction sequence specific primers(PCR SSP) for genotyping of ABO blood group and observation ABO gene polymorphism as well as identification of doubt sample.Results:The reliability of the genotyping for ABO blood group was proved by testing DNA samples previously known genotypes.The results of genotyping for 104 healthy and unrelated HAN individuals were correspond with serological phenotypes.The method of ABO genotyping was applied for clinical pre transfusion ABO typing,pre delivery fetal ABO typing,parenting test and subgrouptyping.Conclusion:The method of ABO genotyping may correct typing for doubt sample of ABO serological typing.
