Treatment of malignant pleural effusion using S_(311) anticancer vaccine by intrapleural injection
- VernacularTitle:S_(311)抗癌菌苗治疗癌性胸腔积液的临床研究
- Author:
Guoxin MAO
;
Zhijian YU
;
Mingzhi ZHAI
;
- Publication Type:Journal Article
- Keywords:
malignant pleural effusion;
S 311 anticancer vaccine;
cisplatine
- From:
China Oncology
2001;0(02):-
- CountryChina
- Language:Chinese
-
Abstract:
Purpose:To evaluate the efficacy of treating malignant pleural effusion with S 311 anticancer vaccine by intrapleural injection.Methods:62 cases with malignant pleural effusion,after drainage, S 311 anticancer vaccine 0.16 mg was injected into the pleural cavity in therapy group (T),and cisplatine 40 mg/m 2 in control group (C).The treatment was repeated after a week , then the efficacy, quality of life, survival rate and toxicities was evaluated.Results:The response rate was 90.6% in T group and 60.0% in C group. There was statistical difference between the two groups ( P