The influence of tapasin on HLA-E expression on cell surface
- VernacularTitle:Tapasin对HLA-E细胞表面表达的影响
- Author:
Liang ZHAO
;
Lian FAN
;
- Publication Type:Journal Article
- Keywords:
HLA E Tapasin T2 cell TAP
- From:
Chinese Journal of Immunology
1985;0(02):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To explore the influence of chaperone tapasin on HLA E expression on cell surface.Methods:The infection method was used to transfer the recombinant retrovirus expression vector which was constructed with HLA E molecules on target cells was detected with FACS technique.Results:Exogenous HLA E expression on T2 cell surface was detected with 74.13% and no HLA E expression was detected on control cells and that was transfected with empty vector.Conclusion:It is possible that the expression of HLA E molecules on cell surface involves in TAP independent mechanism.
