OBSERVATION OF PERIOPERATIVE EXPRESSION OF PLATELET GLYCOPROTENIN CD_( 41) AND CD_(62P) IN GASTRIC CANCER BY IMMUNE ELECTRON MICROSCOPY
- VernacularTitle:围术期胃癌患者血小板膜糖蛋白的免疫电镜观察
- Author:
Xinnong LIU
;
Yongjian XU
;
Qinghong LIU
;
- Publication Type:Journal Article
- Keywords:
Gastric cancer;
Platelet glycoprotein;
Platelet activation;
Immune electron microscopy
- From:
Cancer Research and Clinic
2000;0(06):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To observe the preoperative changes of human platelet glycoprotein CD 41 and CD 62P in gastric cancer,aiming to laying the foundation for studying the relation between the changes of formation and constitution of CD 41 and CD 62P and cancerous growth and transition,meanwhile,maintaining the basis for the prevention of thrombotic disease after operation.Methods:Immune electron microscopy was applied to study the changes of CD 41 and CD 62P in 9 cases of gastric cancer and in 5 cases of normal group.Results:Compared with normal group,the contents of CD 41 and CD 62P in gastric cancer were increased,and got more during operation,especially got most in 30 minutes after operation.The changes of CD 41 and CD 62P were observed not only in quantity but also in formation and constitution.Conclusion:Platelets are activated in patients with gastric cancer before operation.Operation can further activate human platelets.
