Changes of the expression of CD28+ and activation of various population of T cell in peripheral blood from lung cancer patients
- VernacularTitle:肺癌患者外周血T淋巴细胞及亚群CD28表达和活化的改变
- Author:
Hailin FENG
;
Yiren LIANG
;
Jiangjiang ZHANG
;
- Publication Type:Journal Article
- Keywords:
Lung cancer Peripheral blood T cells CD28
- From:
Chinese Journal of Immunology
2000;0(11):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To investigate the changes of expression of CD28 on T cells and activation of various population of T cells in peripheral blood of lung cancer patients and to study the relations of these changes with clinical stages.Methods:Three color immunofluorence staining and flow cytometry was used to detect the expression of CD28 on various population of T cells and the activation of CD28+ T cells in peripheral blood both of 38 normal persons and 42 patients with lung cancer.Results:Comparing blood of lung cancer patients were remarkably decreased(P
