Observation on blood-brain barrier around hematome in patient with hypertensive cerebral hemorrhage
- VernacularTitle:高血压脑出血血肿周围组织血-脑屏障变化的动态观察
- Author:
Linsen DOU
;
Qidong CHEN
;
Wei LI
;
Al ET
- Publication Type:Journal Article
- Keywords:
Hypertension;
Cerebral hemorrhage;
Bloo d-brain barrier;
Microscopy, election
- From:
Chinese Journal of Neurology
2000;0(05):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To evaluate blood-brain barrier around the hematoma in patients harin g hypertensive cerebral hemorrhage. Methods Tissues from blood-brain barrier around t he hematoma were collected, and at the same time to cerebeal hemorrha gic patients the hematoma extracting. Results Within asuper early peroid (7 hours) and acute peroid (72 hours) a nd subacute peroid (4~7 days) of the cerebral hemorrhage, the tissues of blood-brain barrier observed under electronic micrscop e, showed that the damagement of the blood-brain barrier was increas ed in direct proprotion to the length of time and the patients presenting a relevant clinical manifestation mean-while.Conclusion The changes of blood-brain berrier is more importment for a t imely treatment, and a hemotoma extracting is suggested as to improving the live qua lity of patients.