Research on Micronucleus Frequency and Chromosomal Aberration in Peripheral Blood Lymphocytes of Subjects With Endemic Arsenism in Xinjiang
- VernacularTitle:新疆地方性砷中毒患者外周血淋巴细胞微核率及染色体畸变研究
- Author:
Ling KANG
;
Hua YAO
;
Biyu XIAO
;
Al ET
- Publication Type:Journal Article
- Keywords:
Arsenic;
Poisoning;
Micronuleus;
Chromosomal aberration
- From:
Journal of Environment and Health
1992;0(04):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To explore the long term mutagenic and carcinogenic effects of endemic arsenism Methods The micronuclei and chromosomal aberration in peripheral blood lymphocytes were detected by conventional micro whole blood culture method among 112 subjects with endemic arsenism and 88 healthy residents as controls Results Significantly higher frequencies of chromosomal aberrations(1 0770‰?0 1953%) and micronuclei(0 8547‰?0 0567‰) of peripheral blood lymphocytes were observed in arsenic poisoned group compared with those(0 4286‰?0 1241%,0 3928‰?0 0368‰) of controls respectively ( P
