The antitumor efficacy of Heplipin on S37 sarcoma and B16 melanoma in mice
- VernacularTitle:肝脂素对小鼠S37肉瘤与B16黑色素瘤的抗肿瘤作用
- Author:
Yi QIAO
;
Jianping LU
;
Jianqun MAO
;
Al ET
- Publication Type:Journal Article
- Keywords:
anti cancer remedy;
heplipin;
mice transplanted tumor
- From:
China Oncology
2001;0(03):-
- CountryChina
- Language:Chinese
-
Abstract:
Purpose:To investigate inhibitory effect of Heplipin on the growth of S37 and B16 implanted into Kunming and C57 mouse respectively. Methods:Heplipin was administrated through gastric inhabatin with the dose of each day such as 3 000 mg/kg (large dose group) 1800 mg/kg(medial dose group) and 1100 mg/kg different (small dose group). Cycolo phosphaincole(CTX, each day 20 mg/kg) and normal saline wasused as postive and negative control respectively. The rates in tumor inhibition, the number of blood vessels, and the rate of necrosis area was tested.Results:The growth suppression of Heplipin to S37 sarcoma and B16 melanoma was 75.1% (large dose, P
