Clinical analysis of chemotherapy plus radiotherapy in locally advanced nasopharyngeal carcinoma
- VernacularTitle:诱导化疗加放射综合治疗局部晚期鼻咽癌的临床分析
- Author:
Tao WANG
;
Gong CHENG
;
Yunfeng ZHOU
;
- Publication Type:Journal Article
- Keywords:
Nasopharyngeal carcinona;
Radiotherapy;
Chemotherapy
- From:China Oncology
2001;0(03):-
- CountryChina
- Language:Chinese
-
Abstract:
Purpose:To study the influence of chemotherapy on radiotherapy in locally advanced nasopharyngeal carcinoma. Methods:96 patients with histologically proven nasopharyngeal carcinoma in stages Ⅲ,Ⅳ were divided randomly into two groups. Radiotherapy group (48 cases) only received radiotherapy with DT66—76Gy in nasopharynx and DT50—70Gy in the neck. Chemoradiotherapy group (48 cases) received chemotherapy with cisplatin and 5 fluorouracil before the same radiotherapy as the radiotherapy only group. Results:The 1,3,5 year survival rates were 94.2%,72.9%,65.7% in chemoradiotherapy group and 89.1%,56.8 %,46.8% in radiotherapy group respectively, with significant difference between the two groups ( P
