Three different dividing dosage of DDP combined with chemotherapy to treat moderate and advanced tumors
- VernacularTitle:顺铂三种剂量分配联合化疗治疗中晚期肿瘤
- Author:
Jiuguang YIN
;
Dongmei JI
;
- Publication Type:Journal Article
- Keywords:
DDP;
three different usages;
curative effect;
sick and vomiting;
kidney toxicity
- From:
China Oncology
2001;0(03):-
- CountryChina
- Language:Chinese
-
Abstract:
Purpose:To ascertain the curative effect and side effects from three different dividing dosage of DDP. Methods:315 cases of moderate and advanced tumors mainly treated with DDP and combined with chemotherapy were divided into 3 groups: (1)DDP 100 ml once(none divided group);(2) 30 to 40 ml of DDP per day, using continuously for 2 to 3 days(middle divided group); (3) 20 ml of DDP per day, using continuously for 5 days(small divided group). And 1 to 3 kinds of other chemotherapy medicines were used at same time. After using the above medicines, the curative effect, main reaction of nausea and vomiting and kidney toxicity were analysed. Results:The curative effect is better in group 1 and 2,but not so good in groups 3. The reaction of nausea and vomiting is slight in the group 2, and the kidney toxicity is high in group 1. Conclusions:The group 2 gets a good curative effect and only slight side effects, and is easy to apply. [
