RELATION BETWEEN THE EXPRESSION OF PROLIFERATING CELL NUCLEAR ANTIGEN AND PROGNOSIS IN LUNG SQUAMOUS CELL CARCINOMA
- VernacularTitle:增殖细胞核抗原与肺鳞状细胞癌临床病理特征的相关性
- Author:
Pinxian SI
;
Yuhao YANG
;
Deqiong DONG
;
- Publication Type:Journal Article
- Keywords:
Lung carcinoma;
Squamous cell Carcinoma;
PCNA;
Prognosis
- From:
Cancer Research and Clinic
1997;0(03):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To investigate the relation between the expression of proliferating cell nuclear antigen (PCNA) and prognosis in lung squamous cell.Methods:The expression of PCNA on 51 cases carcinoma tissues were detected by immunohistochemical SP technique. Thet test and F test was used to analyze the difference of expression of PCNA in different pathological grades and clinic stages.Spearman Grade-relation test was used to analyze the relation between PCNA expression and pathological grades.The difference of survival time was compared by Kaplan-Meier curve and Long-rank test in different PCNA expression.Rusults:The position of PCNA expression almostl located in the nuclear,some in cytoplasm.There was difference of PCNA expression in different clinical stages and pathological grades.( P