Establishment of in vitro cellular model predicting histocompatibiliy in allograft
- VernacularTitle:建立预测同种异体间组织相容性细胞模型
- Author:
Youhua HAO
;
Xiongwen WU
;
Zhihui LIANG
;
Al ET
- Publication Type:Journal Article
- Keywords:
Allograft Histocompatibility Model of histocompatibility
- From:
Chinese Journal of Immunology
1985;0(06):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To develop a new model of evaluating histocompatibility between donor and recipient.Methods:①We harvested 15 couples of blood samples of donor and recipient in human BMT and detected histocompatibility between donor and recipient using the aboved model.The time when GVHR began was recorded.②Skin grafts of KunMing hybride mice were respectively placed on inbred mice,BALB/c and C57BL/6.And then histocompatibility between donor and recipient was detected using the model.Survival time of skin allografts was recorded.Results:The smaller differences of histocompatibility evaluated by means of the model were,the later GVHR in human BMT would happen and the longer survival time of skin allografts in mice would become.Conclusion:The model could be used to detect correctly histocompatibility between donor and recipient.
