Subdiaphragmatic vagotomy reduce the responses of fever and c-Fos expression in rat PVN and NTS to LPS
- VernacularTitle:膈下迷走神经切断降低LPS所致大鼠发热及室旁核、孤束核c-Fos蛋白表达
- Author:
Xiuying LU
;
Guizhen YANG
;
- Publication Type:Journal Article
- Keywords:
Vagus nerve c Fos PVN NTS IL 1 Fever
- From:
Chinese Journal of Immunology
1986;0(04):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To study the possibility that responses of fever and c Fos expression in rat PVN and NTS to intraperitoneal administration of LPS are mediated by vagal afferents.Methods:Rectal temperature was detected by digital temperature detecting instrument.c Fos expression was detected by immunohistochemistry staining.Results:The rectal temperature change value in vagotomy LPS group was significantly decreased compared with that in sham LPS group,and there was striking difference between them,P
