Influence of total polysaccharide extracted from Sijunzi decoction on the intestinal mucosa associated lymphoid tissues of mice
- VernacularTitle:四君子汤复方总多糖对小鼠肠道粘膜相关淋巴组织的影响
- Author:
Liang LIU
;
Hua ZHOU
;
Peixun WANG
;
Al ET
- Publication Type:Journal Article
- Keywords:
Sijunzi decoction Total polysaccharide Intestinal mucosal immune Cyclophosphamide
- From:
Chinese Journal of Immunology
1986;0(04):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective:By using the model of intestinal mucosal associated lymphoid tissue injury by cyclophosphamide, to understand the influence of total polysaccharide extracted from Sijunzi decoction (TPSJ) on the intestinal mucosal associated lymphoid tissue which reflect the status of the intestinal mucosal immune of mice Methods:Investigate the effects of TPSJ to the number of Peyer's patches of mice, total cell number of Peyer's patches, the number of CD3 + and IgA + cell, apoptosis at 24 h after being treated with 100 mg/kg cyclophosphamide Results:TPSJ could increase the number of Peyer's patches of mice, total cell number of Peyer's patches, the number of CD3 + and IgA + cell, and could reduce apoptosis as well Conclusion:TPSJ could antagonize the injury of intestinal mucosal associated lymphoid tissues of mice induced by cyclophosphamide, suggesting that this polysaccharide can improve the intestinal mucosal immunofunction
