The design and prediction of biology characteristics of recombinant toxin CD80-Linker-SEA
- VernacularTitle:人CD80-Linker-SEA重组毒素的设计及生物学特性预测
- Author:
Zengshan LI
;
Yanfang SUI
;
Yongqiang JIANG
;
Al ET
- Publication Type:Journal Article
- Keywords:
Recombination CD80 Staphylococcal enterotoxin A(SEA) Computer analysis
- From:
Chinese Journal of Immunology
1985;0(01):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To construct the eukaryotic expressed vector which express recombinant toxin CD80 Linker SEA and predict the rationality and feasibility of the linker Methods:Utilize the sequence analysis software to analyze the flexibility、antigenicity、Hoop&Woods hydrophilicity and episode of recombinant toxin CD80 Linker SEA Results:Through the analysis of the software,it could be found that the recombinant toxin has correct domains of CD80 and SEA The linker has low episode、low antigenicity and high flexibility Conclusion:The results of computer analysis could help us to rationally design the recombinant toxin CD80 Linker SEA and keep it's maximum biological activity
