Changes of preoperative and postoperative NK and T lymphocyte with gastric cancer
- VernacularTitle:胃癌患者手术前后NK及T细胞的改变
- Author:
Jun AI
;
Jinrong REN
;
Xueli ZHANG
;
Al ET
- Publication Type:Journal Article
- Keywords:
gastric cancer;
cell immunefunction;
T lymphocyte subsets;
NK cell activity
- From:
China Oncology
2000;0(06):-
- CountryChina
- Language:Chinese
-
Abstract:
Purpose:The aim of this study was to evaluate the changes of NK and T lymphocyte with gastric cancer and before and after operation.Methods:T lympho cyte subsets and NK cell activity of 36 cases of gastric cancer and 30 cases of normal subjects were measured by monoclonal anti human T lymphocyte antibody and MTT assay before and after operation.Results:It was found that before operation the CD3(+),CD4(+) cell and ratio of CD4(+)/CD8(+) were significantly decreased and CD8(+) cell was increased and NK activity decreased with gastric cancer as compared to control group ( P
