Low dose fluorouracil and cisplatin continuous infusion for the treatment of advanced gastric carcinoma
- VernacularTitle:低剂量氟尿嘧啶及顺铂持续输注治疗晚期胃癌的近期疗效
- Author:
Wangkun LU
;
Xinhua HUANG
;
Lifang XU
;
Al ET
- Publication Type:Journal Article
- Keywords:
FU;
DDP;
chemotherapy;
advanced gastric carcinoma
- From:
China Oncology
2000;0(06):-
- CountryChina
- Language:Chinese
-
Abstract:
Purpose:To evaluate the efficacy and toxicity of the low dose 5 Fluorouracil and Cisplatin continuous infusion for treatment of advanced gastric carcinoma. Methods:A total of 21 patients were enrolled in the trial, FP therapy consisted of 5 FU (0 25/m 2/d) every day by continuous infusion and cisplatin (6 mg/m 2/d) every day by continuous infusion for 3 weeks.Results:A complete response was observed in 2 cases and a partial response in 10 cases, for and overall response rate of 57.1%. Toxic effects included leukopenia, thrombocytopenia, nauesa and vomiting.Conclusions:FP therapy is a promising regimen for patients with advanced gastric carcinoma.
