Treatment of olfactory neuroblastoma with surgery plus irradiation——a report of 14 cases
- VernacularTitle:手术加放射治疗嗅神经母细胞瘤14例
- Author:
Liting QIAN
;
Guangyuan CHENG
;
- Publication Type:Journal Article
- Keywords:
olfactory neuroblastoma;
surgery;
radiotherapy
- From:China Oncology
2000;0(06):-
- CountryChina
- Language:Chinese
-
Abstract:
Purpose:To evaluate the effects of surgery plus irradiation for olfactory neuroblastoma Methods:From January 1975 to February 1998 fourteen patients with olfactory neuroblastoma (kadish dassification:One case in stage A, 8 in the Stage B, 5 in stage C) were resected and giver radiotherapy to an average dose of 6000 cGy to primary lesions.Results:Six of the 14 patients have been living for 2—24 years. 8 died (5 of recurrence and 3 of distant metastasis)in 6 months to 4 years after diagnosis.Conclusions: There is a high rate of pathologic misdiagnosis in olfactory neuroblastoma. Immunohistologic examination and electron microscopic study are benifitial for diagnosis. Surgery plus irradiation is a suitable method for olfactory neuroblastoma. Radiotherapy is able to reduce local recurrence after surgery and increase resectability rate as well as to control distant metastasis.
