Ifosfamine and etoposide in 26 cases with relapse ovarian carcinoma
- VernacularTitle:异环磷酰胺与依托泊苷联合治疗26例复发卵巢癌
- Author:
Zhimei WANG
;
Xiuhua SUN
;
Ruifei WANG
;
- Publication Type:Journal Article
- Keywords:
relapse ovarian carcinoma;
ifosfamide;
etoposide
- From:
China Oncology
2000;0(06):-
- CountryChina
- Language:Chinese
-
Abstract:
Purpose:To investigate the treatment effect and toxicity of regimen containing ifosfamide (IFO) and etoposide (VP16) on relapse ovarian carcinoma.Methods:IFO 2.0 in 500 ml normal saline day 1—5, VP16 100 mg in 500 ml normal saline d1,3,5 Results:The overall response rate was 38.5%, mylosuppression and alopecia were the most common toxicities. Leukopenia rate was 71.4%, alopecia rate was 100%, gastro intestinal and nervous toxicity were mild. Conclusions:Combination of IFO and VP16 was very effective on relapse ovarian carcinoma with mild toxicity and should be widely used.
