THE EXPRESSION OF GLUTATHIONE S-TRANSFERASES (GST-?) IN GASTRIC CARCINOMA
- VernacularTitle:胃癌中谷胱甘肽S-转移酶的表达
- Author:
Lianxin LIU
;
Xin QU
;
Anlong ZHU
;
Al ET
- Publication Type:Journal Article
- Keywords:
Gastric neoplasm;
Glutathione S-transferases;
GST-?;
immunohistochemistry
- From:
Cancer Research and Clinic
1999;0(05):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To study the clinical significance of glutathione s-transferases expression ingastric carcinoma tissues. Methods The expression of 98 gastric carcinoma was studied by means ofimmunohistochemical technique. Results The glutathione S-transferases were between 25. 0% and 88. 9%in 98 cases of gastric carcinoma. The GST-? was significantly higher in the cases of poorly differentiatedthan those of well differentiated. But it was not correlated with patient age, sex, tumor size, tumor'slocation,and lymph node metastases. Conclusion The determination of GST-? may be useful for diagnosis,prognosis and treatment of gastric carcinoma.
