Calcium-dependent modulatory effect of norepinephrine on the Ia antigen expression of the macrophage
- VernacularTitle:去甲肾上腺素调控巨噬细胞Ia抗原表达的钙依赖性
- Author:
Jian-Jun HUANG
;
Fei-Li GONG
;
Xin-Wei FENG
;
- Publication Type:Journal Article
- Keywords:
Macrophage;
Calciumion;
Ia antigen;
Norepinephrine
- From:
Chinese Journal of Immunology
1985;0(06):-
- CountryChina
- Language:Chinese
-
Abstract:
Fura—2 was used as a Ca~(2+) indicator to determine the intracellular calcium ion concentra-tion(〔Ca~(2+)〕i)of rat peritoneal macrophages(RPM?s),and APAAP enzyme immnoassay was ap-plied to detect the expression of Ia antigens on RPM?s.The results showed that norepinephrine(NE,10~(-9)mol/L)could markedly increase the〔Ca~(2+)〕i of the RPM?s(p
