A Preliminary study on serum Anti—Human—Chromosome Antibodies
- VernacularTitle:血清抗人染色体抗体的初步研究
- Author:
Xiao-Hui JI
;
De-Hua KOU
;
Yuan GU
;
Shu-Yun YUAN
;
Wenping DU
;
Kaiti WU
;
Yiwen RONG
- Publication Type:Journal Article
- Keywords:
chomosome;
antibodies;
systemic lupus erythematosus;
immunoassay;
immunogold-silver staining
- From:
Chinese Journal of Immunology
1985;0(05):-
- CountryChina
- Language:Chinese
-
Abstract:
With human chromosomes,as antigen,anti—human—chromosome antibodies (AhChrA)were detected specifically from SLE patients sera by the methods of immunogold—silver staining(IGSS)and immnuofluorescenee tese (IFT)。To SLE,the sensitivity and specificity of serumAhChrA was 58.1%and98.5%respeetively in IGSS,34.9%and99.5%respectively in IFT。Boththe incidence and titer of AhChrA were found to be colsely related to the pathoactivity and thedamages of some important organs or tissues,such as kidney damage,abnormal immunity andhematocytopenia.A preliminary analysis of the antigen components reacting to AhChrA was alsoperformed。
