The effect of amygdaloid nuci ei on immunogical function induced by stress
- VernacularTitle:杏仁核损毁拮抗应激介导免疫抑制效应的实验性研究
- Author:
Cheng QIAN
;
Gui-Zhen YANG
;
- Publication Type:Journal Article
- Keywords:
Amygdaloid nuclei;
Amputation operation stress;
Cell-mediated immunity. Corticosterone;
Methionine-enkephalin
- From:
Chinese Journal of Immunology
1986;0(04):-
- CountryChina
- Language:Chinese
-
Abstract:
Rat with amputation operation stress possessed a decline of NK activity and splenocyte pro-liferation to mitogen ConA.Amygdaloid nuclei lesion could antagonize the decrease of those ofcell-mediated immunity.Further results showed that serum corticosterone and methionine-enkephahn was high in stress' rats.Amugdaloid Nuclei lesion could antagonize the increase ofserum corticosterone level,but seem no dffeet on serum methionine-enkephalin level,thereforesuggesting that it is related to ratio of corticosterone to enkephalin changed by decrease of corti-costerone that amygdaloid neuclei lesion antagonized the decline of immunogical function inducedby stress.