Analysis of DNA polymorphism of HLA—DQ locus with PCR/SS0 in Hunan Hans
- VernacularTitle:应用PCR/SSO方法分析湖南藉汉族人HLA—DQ位点DNA的多态性
- Author:
Xiuwu ZHANG
;
Shishi GUO
;
- Publication Type:Journal Article
- From:
Chinese Journal of Immunology
1985;0(01):-
- CountryChina
- Language:Chinese
-
Abstract:
Abstract In this paper,the sequences of second exon of DQA1 and DQB1 were amplified byPCR primers,and hybridized with 17 or 23 sequence specific oligonucleotide probes labeled byisotope respectively.The distribution of 10 DQA1 alleles and 17 DQB1 alleles was observed inHunan Hans population.The results showed that the most of DQAI and DQB1 alleles were ex-pressed in Hans,however,their frequencies are different from Caucasoids.
