Clinical study on anti—SSA antibody by using dot immunobinding assay
- VernacularTitle:点—免疫结合法检测抗SSA抗体的临床研究
- Author:
Ming JING
;
Shujie ZHOU
;
Zhongchen KOU
;
Chunli YAN
- Publication Type:Journal Article
- Keywords:
Dot immunobinding assay;
Anti—SSA antibody;
Sjogren syndrome
- From:
Chinese Journal of Immunology
1985;0(05):-
- CountryChina
- Language:Chinese
-
Abstract:
Using human spleen purified SSA antigen,we set up a new technique of dot immunobinding assay(DIBA)for detection of anti—SSA antibody.The specificity of DIBA is better than that of double immunodiffusion method.The positive rate of anti—SSA antibody in Sjogren syndrome is 76.9%,while that in systemic lupus erythematosus is 33.3%.We found that anti—SSA antibody and RF usually appeared in same patient with Sjo-gren syndrome or rheumatoid arthritis.
