DETERMINATION OF THYROID-STIMULATING ANTIBODIES WITH CYCLIC AMP ACCUMULATION INDUCED BY UNFRACTIONATED SERUM USING CULTURED HUMAN THYRIOD CELLS
- VernacularTitle:用不提取血清刺激人甲状腺细胞cAMP的生成测定甲状腺刺激性抗体
- Author:
Guo-Chun LUO
;
Zhang-Yudept PAN
;
- Publication Type:Journal Article
- Keywords:
Thyroid-stimulating antibody Graves' disease Simple thyroid goitre Thyroid adenoma
- From:
Chinese Journal of Endocrinology and Metabolism
1986;0(03):-
- CountryChina
- Language:Chinese
-
Abstract:
Thyroid-stimulating antibodies were determined with cyclic AMP accumulation induced by unfractionaled serum using cultured human thyroid cells. Thyroid-stimulating antibodies were found in 83.3% (25/30) of patients with Graves' disease without treatment, 43.8% (7/16) of patients with Graves' disease during antithyroid treatment, 4% (1/25) of normal people and none of patients with simple goitre or thyroid adenoma. The results indicate that determination of thyroid-stimulating antibodies using this method is sensitive and characteristic in patients with Graves' disease.
