GNRH NEURONS AND THEIR PATHMAYS IN THE BRAINS OF RATS AND MICE——AN IMMUNOHISTOCHEMICAL STUDY.
- VernacularTitle:大鼠和小鼠脑内的GnRH神经元及其纤维通路——免疫组织化学研究
- Author:
Tianbao SONG
;
Qianwu LI
;
- Publication Type:Journal Article
- Keywords:
hypothalamus;
gonadotropin-releasing hormone;
immunohistochemistry;
rat;
mouse
- From:
Journal of Xi'an Jiaotong University(Medical Sciences)
1981;0(02):-
- CountryChina
- Language:Chinese
-
Abstract:
By means of ABC immunoenzyme technique, the distribution of GnRH neurons and fibers in the brains of rats and mice was observed, The results showed that more than 90% of GnRH neuronal perikarya were concentrated in the diagonal band-medial preoptic area near the organum vasculosum lamina terminalis, extending rostro-dorsally to the medial septic nucleus and caudo-laterally to the supraoptic nucleus region. No GnRH cell body could be found in the mediobasal hypothalamus, GnRH fibers terminated in the median eminence via the periventricular and lateral tracts. In the rostral median eminence, fibers were present in its entire layers and width, and caudally separated into two laterally-located bundles. The difference of GnRH system between rodents and primates, as well as its significance in reproduction are discussed.
