CLINICAL SIGNIFICANCE OF TMAb AND TGAb MEASURED WITH ENZYME-LINKED IMMUNOSORBENT ASSAY

VernacularTitle:ELISA测定TMAb和TGAb的临床意义
Author: Ling WANG ; Wu-Fei ZHENG ;
Publication Type:Journal Article
Keywords: ELISA TMAb TGAb Thyroid disease
From: Chinese Journal of Endocrinology and Metabolism 1985;0(02):-
CountryChina
Language:Chinese
Abstract: The serum thyroid microsomal antibodies (TMAb) and thyroglobulin antibodies (TGAb) were measured in 103 normal persons and 183 patients with different thyroid diseases by enzyme-linked immunosorbent assay (ELISA). The serum T3 and T4 were also tested. The results showed that the incidence of these two autoantibodies were obviously increased in Hashimoto's thyroiditis, hyperthyroidism and hypothyroidism, and normal in simple goiter and thyroid adenoma. The TMAb and TGAb levels in subacute thyroiditis and thyroid cancer were moderately increased. There were also a negative correlation between TMAb and T3, T4, TGAb and T4 in Hashimoto's thyroiditis.