RELATIONSHIP BETWEEN APOLIPOPROTEIN E ISOFORMS AND HYPERLIPIDEMIA IN PATIENTS WITH ABNORMAL GLUCOSE TOLERANAE
- VernacularTitle:糖耐量异常患者ApoE表型与高脂血症关系
- Author:
Xiao-Hu WANG
;
Xiao-Ren PAN
;
- Publication Type:Journal Article
- Keywords:
Apolipoprotein E isoforms Diabetes mellitus Impaired glucose tolerance Hyperlipoproteinemia
- From:
Chinese Journal of Endocrinology and Metabolism
1985;0(02):-
- CountryChina
- Language:Chinese
-
Abstract:
This paper studied the relationship between apolipoprotein E isoforms and hyperlipidemia among 92 cases of diabetes mellitus, 174 cases with impaired glucose tolerance and 124 sex-age-matched controls. The results demonstrated that the patients with abnormal glucose tolerance had higher frequency of E2/3 isoforms and lower frequency of E, / , in com parison with controls. Hyperlipoproteinemia were mainly related to hyperglycemia but the Apo E isoforms which ex pressed different alleles also associated with hyperlipoproteinemia.
