EVALUATION FOR EFFECTS OF LOPID AND FENOFIBRATE ON LIPIDS METABOLISM
- VernacularTitle:降脂药诺衡和非诺贝特治疗NIDDM脂代谢紊乱疗效评价
- Author:
Yanliang LI
;
JIN-ZHONG
;
- Publication Type:Journal Article
- From:
Chinese Journal of Endocrinology and Metabolism
1986;0(04):-
- CountryChina
- Language:Chinese
-
Abstract:
Effects of Lopid and Fenofibrate on serum lipids, lipoproteins, apolipoproteins were studied in 22 diabetic patients with dyslipidaemia. The levels of FBG, HBA1, lipids, lipoproteins and apolipoproteins were determined before treatment, 3 weeks and 6 weeks after treatment. The results showed: 1). Lopid lowered the levels of TC, HDL-TG,TG,apoB100 and raised the levels of HDL-C, apoA-I significantly.2). Fenofibrate lowered the levels of TG, TG, HDL-TG, apoB100 and raised the level of HDL-C, but no effect on apoA-I. Comparing the efficacy of these two drugs on lipids metabolism, i seems that Lopid is better than Fenofibrate. Both of the drugs can be well tolerated by most diabetic patients.
