THE CHANGING FEATURES OF TXB_2 AND 6-KETO-PGF_(la) IN THE INHABITANTS AT HIGH ALTITUDE
- VernacularTitle:高原居民血浆TXB_2与6-酮-PGF_(1?)的变化特点
- Author:
Zhirui LI
;
Guotong LI
;
- Publication Type:Journal Article
- From:
Chinese Journal of Endocrinology and Metabolism
1985;0(01):-
- CountryChina
- Language:Chinese
-
Abstract:
Serum TXB2 and 6-keto-PGF1a were measured with radioimmunoassay in the inhabitants at an altitude of 3,100 m above sea-level (Group I) and the aged who had returned to places at sea-level after retirement (Group II), and the subjects living in the Xian plain served as controls. The results showed that (1) both serum TXB2 and TXB2 / 6-keto-PGF1a ratio increased obviously in Group I; (2) serum TXB2 dropped rapidly in Group II. It may be suggested that anoxia be the key-factor in causing the changes mentioned above, and that the increase in serum TXB2 be one of the main factors leading to pulmonary hypertension seen in patients living at high altitude and it may be closely related to a number of diseases.
