THE DETECTION OF PROTEINURIA IN DIABETIC NEPHROPATHY AND ITS PATHOGENESIS
- VernacularTitle:糖尿病肾病尿蛋白检测的实验研究及发生机理探讨
- Author:
Yerong YU
;
Jinzhong LIANG
;
- Publication Type:Journal Article
- From:
Chinese Journal of Endocrinology and Metabolism
1986;0(04):-
- CountryChina
- Language:Chinese
-
Abstract:
Sixty diabetic patients and twenty normal controls were studied. The results showed that: 1) Counter-immuno-electrophoresis is a sensitive and simple test suitable for the detection and monitoring of diabetic microproteinuria; 2) The proteinuria in diabetic nephropathy is glomerular in origin which is supported by the finding of a marked increase in urinary albumin excretion and a normal level of urinary ?2-microglobulin; 3) The serum ?2-microglobulin appears to be a more sensitive index than serum creatinine and creatinine clearance rate for the detection of impairment of renal function in diabetic patients; 4) Diabetic nephropathy is related to glycemic control and duration of diabetes mellitus.
