Effects of Murine Thymic Epithelium Cultural Supernatant on Spontaneous and ConA-Stimulated Proliferation of Thymocytes
- VernacularTitle:小鼠胸腺上皮细胞培养上清对胸腺细胞增殖反应的作用
- Author:
Baiqing LI
;
Guizhen YANG
;
- Publication Type:Journal Article
- Keywords:
Thymic Epithelium;
Prolierative Exponent;
Thymocyte Proliferation Cultural Supernatant.
- From:
Chinese Journal of Immunology
1985;0(05):-
- CountryChina
- Language:Chinese
-
Abstract:
Cultivation of murine thymic epithelium has been established.Murine thymic epi-thelial cultural supernatant showed activity increasing both spontaneous ~3H-TdR inco-rporation and ConA-stimulated proliferation of thymocytes by the exponent of 1.5-2at dilution 1:8 to 1:32,the peak of the activity was present at 10-20 or 15 days ofcultivation.However,the thymic epithelial supernatant from cultures at 6-7 daysshowed activity suppressing both proliferations of thymocytes at dilution 1:8-1:16.Theresult showed thymic epithelial supernatant had no 1L-2 activity.
