THE THERAPEUTIC EFFECT OF PROPRANOLOL COMBINED WITH METHIMAZOLE IN HYPERTHYROIDISM
- VernacularTitle:心得安与他巴唑联合治疗甲状腺机能亢进症的近期疗效观察
- Author:
Yijie WU
;
Zhongfu SHI
;
- Publication Type:Journal Article
- From:
Chinese Journal of Endocrinology and Metabolism
1985;0(01):-
- CountryChina
- Language:Chinese
-
Abstract:
Ninty-nine initial but untreated patients with hyperthyroidism were divided at random into three groups :propranolol, methimazole, and combined groups. Determination of serum T4, T3, rT3 and TSH levels together with STI and ICG were performed before and during treatment among these groups. The results showed that in the combined group, the fall of mean T3 levels to normal was the earliest and fastest, there was a better normalization of cardiac parameters, and the clinical manifestations could be brought under control rapidly. The combined therapy of propranolol with methimazole was especially advantageous to cases of mild and moderate hyperthyroidism.