Detection of anti-dsDNA antibody in SLE patients by enzyme marking staphylococcal protein A (SPA)
- VernacularTitle:用酶标记金葡菌A蛋白检测SLE患者抗dsDNA抗体的研究
- Author:
Lu-Nan WANG
;
Shu-Qing LI
;
- Publication Type:Journal Article
- Keywords:
SPA Anti-dsDNA
- From:
Chinese Journal of Immunology
1985;0(01):-
- CountryChina
- Language:Chinese
-
Abstract:
The results of the detection of fhe antibody against dsDNA in 244 sera by immunohisto—chemical method of enzyme marking SPA were reported and compared with immunoflurescence assay and enzyme marking antibody method. Positive rate in 31 cases with SLE was 71%. Of the 31 cases 21 with SLE in theactive phase were all positive,1 out of 10 cases at the recovery stage was positive,2 outof 152 cases with other connective tissue and non connective tissue disease were weaklypositive,61 normal persons were all negative.The overall agreement was the same asthe immunofluorescence and enzyme marking antibody method.Enzyme marking SPAmethod offers a number of significant advantageous.This method was easily operated,did not need to prepare second antibody,and special equipment was not needed.It can beused clinically.
