Effect of GPS On Stimulating Murine Lymphocyte Proliferation
- VernacularTitle:甘草多糖对小鼠淋巴细胞的激活增殖效应
- Author:
Yong SHI
;
Gui-Zhen YANG
;
- Publication Type:Journal Article
- From:
Chinese Journal of Immunology
1985;0(05):-
- CountryChina
- Language:Chinese
-
Abstract:
Glycyrrhiza uralensis Fish Polysacchoride(GPS)was observed to have mitogenic activity on murine spleen cell proliferation in vitro,The results showed that this mitogenic activity of GPS may be directed to B Iymphocytes,i.e.GPS is a new mitogen of murine B lymphocytes.Furthermore,it was found that B lymphocytes stimulated by GPS was M? depedent and T cell-indepedent.On the contrary,antibodies and IL-2 production was inhibited by GPS in vivo.