Determination of Genetic Polymorphism of Properdin Factor B in Patients With Graves Disease
- VernacularTitle:Graves氏病人血清补体第二途径B因子遗传多态性的检测
- Author:
Jian-Hua CHENG
;
Xiu-Zhu ZHAO
;
- Publication Type:Journal Article
- Keywords:
Complement) Bf;
Polymorphism;
Graves' Disease.
- From:
Chinese Journal of Immunology
1985;0(03):-
- CountryChina
- Language:Chinese
-
Abstract:
Genetic polymorphism of properdin factor B (Bf)of alternative complement pathway was investigated in 110 patients with Gravesldisease and in 220 blood donors in Wuhan Blood Transfusion Center using high voltage agarose gel electrophoresis andsubsequent immunofixation. Results show that distributions of Bf phenotype observed in normals are in agreement with those expected from the Hardy-Weivr, erg equilibrium (XZ=5.4337, Pc~0.10),but in patients donlt (XZ=29.689~, Pc.
