Initial Selection of Preparation Technology of Liposome from Arnebia euehroma
- VernacularTitle:新疆紫草提取物脂质体制备工艺的初步筛选
- Author:
Li GUOYING
;
MAIERDANMAHEMUTI
;
- Publication Type:Journal Article
- Keywords:
Extracts of Arnebia euehroma;
Liposome;
Preparation technology;
Encapsulation efficiency
- From:
China Pharmacy
2005;0(15):-
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVE:To select the preparation process of liposome of Arnebia euehroma. METHODS:Thin film dispersion method,reverse phase evaporation method,ethanol injection-extrude method,ether injection method and melting methods were used to prepare the liposome of A. euehroma,respectively. The applicability of these five methods was compare with encapsulation efficiency,shapes and the distribution of particles size as indexes. RESULTS:All the methods obtained the liposome in perfect shape and uniform size with the exception of melting method,among which the encapsulation efficiency of liposome reached (63.53?0.71)% by ethanol injection-extrude method. CONCLUSION:The ethanol injection-extrude method is suitable for the preparation of liposome of A. euehroma.
