A Case of Squamous Cell Lung Cancer Representing as Guillain-Barre Syndrome Associated with Monospecific Anti-GD1b IgG.
10.14253/kjcn.2015.17.1.31
- Author:
Yeshin KIM
1
;
Seongheon KIM
Author Information
1. Department of Neurology, Kangwon National University School of Medicine, Chuncheon, Korea. dr.kim94@gmail.com
- Publication Type:Case Report
- Keywords:
Guillain-Barre syndrome;
Paraneoplastic syndrome;
Anti-GD1b antibody
- MeSH:
Aged;
Antibodies;
Ataxia;
Cerebrospinal Fluid;
Guillain-Barre Syndrome*;
Humans;
Immunoglobulin G*;
Immunoglobulins;
Lung Neoplasms*;
Neural Conduction;
Paraneoplastic Syndromes;
Paresthesia;
Polyneuropathies
- From:Korean Journal of Clinical Neurophysiology
2015;17(1):31-34
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
We report a case with squamous cell lung cancer with concomitant Guillain-Barre syndrome (GBS) as a paraneoplastic syndrome. A 67-year-old patient who was previously diagnosed as metastatic squamous cell lung cancer developed mild symmetrical weakness, paresthesia and sensory ataxia. Nerve conduction study showed sensorimotor polyneuropathy. Analysis of cerebrospinal fluid showed high tilter for monospecific anti-GD1b IgG antibody without onconeuronal antibodies. After treatment with intravenous immunoglobulin, the patient's symptoms improved.
