Relationship of VEGF-C expression and lymphatic microvessel density with cervical lymph node metastasis in human laryngeal cancer
- VernacularTitle:喉癌中血管内皮生长因子C和微淋巴管密度的关系
- Author:
Kunpeng MA
;
Jun TIAN
;
- Publication Type:Journal Article
- Keywords:
Laryngeal Neoplasms;
Neoplasms Metastasis;
Immunohistochemistry;
Vascular Endothelial Growth Factor C;
Antibodies;
lymphatic microvessel density
- From:
Chinese Archives of Otolaryngology-Head and Neck Surgery
2006;0(08):-
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVE To analyze the relationship of VEGF-C expression,lymphatic microvessel density and cervical lymph node metastasis in human laryngeal cancer,as well as the relationship of VEGF-C expression and lymphatic microvessel density.METHODS VEGF-C expression and lymphatic microvessel density were detected in 47 laryngeal cancer tissues with SP immunohistochemical method. RESULTS The positive rates of VEGF-C in theⅠ,Ⅱ,Ⅲpathological grade level were 55 %,72.22 %, 88.89% respectively,and its expression was significantly correlated with tumor differentiation(P
