Clinical Observation on 25 Cases of Lupus Nephritis Treated by Chinese Medicines with the Function of Antioxidation
- VernacularTitle:抗氧化中药治疗狼疮性肾炎25例临床观察
- Author:
Yan-Qing TONG
;
Ying WANG
;
- Publication Type:Journal Article
- Keywords:
Chinese herbal medicines;
Antioxidation;
Lupus nephritis
- From:
Journal of Traditional Chinese Medicine
1993;0(05):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To observe the effect of Chinese Medicines with the function of antioxidation on lupus nephritis(LN)pa- tients.Methods The 25 LN patients consisting of renal function normal group(15 cases)and renal failure group(10 cases)were treated with Huang Qi(Radix Hedysari)and Shu Dihuang(Radix Rehmanniae Praeparata)as main ingredients for 6 months in suc- cession.Changes of symptom,systemic lupus erythematosus disease activity index(SLEDAI),activity index(AI),lipid peroxide (LPO),superoxide dismutase(SOD),glutathione peroxide(GSH-Px),malondialchehyche(MDA),nitric oxide(NO),blood and urine routine examination,24-hour urine protein quantity,liver and kidney function,anti-double-stranded DNA(anti ds-DNA),complement 3(C_3)and complement 4(C_4),after treatment were observed.Results SLEDAI and AI scores were remarkably different from those before treatment(P
